Major ALS Breakthrough – Common Cause of All Forms of ALS Discovered
By Dell HillA
major breakthrough has been reported that could soon allow very
specific drug testing to control, or perhaps even eliminate, all forms
of ALS - commonly known as Lou Gehrig's Disease.This outstanding medical news was reported by NeuroScienceNews.com.“The underlying disease process of amyotrophic lateral sclerosis (ALS and Lou Gehrig’s disease), a fatal neurodegenerative
disease that paralyzes its victims, has long eluded scientists and
prevented development of effective therapies. Scientists weren’t even
sure all its forms actually converged into a common disease process.But a new Northwestern Medicine study for the first time has identified a common cause of all forms of ALS.The
basis of the disorder is a broken down protein recycling system in the
neurons of the spinal cord and the brain. Optimal functioning of the
neurons relies on efficient recycling of the protein building blocks in
the cells. In ALS, that recycling system is broken. The cell can’t
repair or maintain itself and becomes severely damaged.The
discovery by Northwestern University Feinberg School of Medicine
researchers, published in the journal Nature, provides a common target
for drug therapy and shows that all types of ALS are, indeed,
tributaries, pouring into a common river of cellular incompetence.“This
opens up a whole new field for finding an effective treatment for ALS,”
said senior author Teepu Siddique, M.D., the Les Turner ALS
Foundation/Herbert C. Wenske Professor of the Davee Department of Neurology
and Clinical Neurosciences at Northwestern’s Feinberg School and a
neurologist at Northwestern Memorial Hospital. ”We can now test for
drugs that would regulate this protein pathway or optimize it, so it
functions as it should in a normal state.”The
discovery of the breakdown in protein recycling may also have a wider
role in other neurodegenerative diseases, specifically the dementias.
These include Alzheimer’s disease and frontotemporal dementia as well as
Parkinson’s disease, all of which are characterized by aggregations of
proteins, Siddique said. The removal of damaged or misfolded proteins is
critical for optimal cell functioning, he noted.This
breakdown occurs in all three forms of ALS: hereditary, which is called
familial; ALS that is not hereditary, called sporadic; and ALS that
targets the brain, ALS/dementia.In
related research, Feinberg School researchers also discovered a new
gene mutation present in familial ALS and ALS/dementia, linking these
two forms of the disease.”Read more about this exciting news by clicking right here.Absolutely
wonderful news from the science of medical research. It’s discoveries
such as this that will one day lead to the prevention or cure for cancer
and other deadly diseases.
Another Credit Downgrade May Happen Sooner Than LaterBy Dell HillWe
saw a minor drop in the unemployment figures this week. That’s a good
thing. But, as most analysts predict, it will be short lived...over and
done with immediately after the holiday season, if not sooner.There’s
one extremely disturbing prediction that made the business news this
week and you haven’t seen or heard about it until now.In
an analyst note, Bank of America/Merrill Lynch Ethan S. Harris says we
should be prepared for at least one more credit downgrade, and perhaps
two! That’s NOT good.Some business insiders are calling this a “bombshell prediction”. Here’s a look at exactly what Harris had to say:“We
expect a moderate slowdown in the beginning of next year, as two small
policy shocks—another debt downgrade and fiscal tightening—hit the
economy. The “not-so-super” Deficit Commission is very unlikely to come
up with a credible deficit-reduction plan. The committee is more
divided than the overall Congress. Since the fall-back plan is sharp
cuts in discretionary spending, the whole point of the Committee is to
put taxes and entitlements on the table. However, all the Republican
members have signed the Norquist “no taxes” pledge and with taxes off
the table it is hard to imagine the liberal Democrats on the Committee
agreeing to significant entitlement cuts. The
credit rating agencies have strongly suggested that further rating cuts
are likely if Congress does not come up with a credible long-run plan.
Hence, we expect at least one credit downgrade in late November or
early December when the super Committee crashes.”Not
only did Harris predict at least one more downgrade, he predicted the
President’s Deficit Commission will be unable to even come close to an
agreement on how to approach the task of eliminating nearly a trillion
and a half dollars of US debt. That’s not good. One major problem that
will cause another major problem.Just
when the holiday shopping season is in high gear, Harris expects the
Deficit Commission to throw up its hands in failure. If that happens,
and another downgrade slams the economy before the end of December, it’s
going to be a VERY long, cold winter everywhere. If you’re watching
the markets closely, you know that investors aren’t exactly burning up
the NYSE computers with “buy orders”. Another downgrade would cause the
word “sell” to echo from the opening to the closing bell.
(Watching All Users Trying To “Friend” Ayman Mansour)
By Dell Hill
If
you happen to be traveling to Egypt, it might not be such a good idea
to post anything bad about Islam to your Facebook account. Freedom of
speech is somewhat lacking in that region, as we learn in this report
from Fox News:
“Egypt's state media says a Cairo court has sentenced a man to three years in prison for postings on Facebook deemed to be inciting sectarianism and in contempt of Islam.
The
MENA state news agency said Saturday the misdemeanor court found Ayman
Mansour had intentionally mocked Islam and used "outrageous and
scurrilous" language in describing the religion's holy book, the Quran,
and its prophet and believers.
The
court said freedom of belief doesn't excuse contempt that may offend
believers and "subject the regime and the country's security to serious
dangers."
Egypt
is grappling with an increasingly assertive ultraconservative Islamist
trend, and recent clashes between the military police and Coptic Christians have heightened fears of increasing sectarian strife.”
It’s
probably a good thing that Facebook users, who are American citizens
and take great pride in their Constitutional Right to Freedom of Speech,
aren’t subject to investigation by the Egyptians. We’d all be in the
slammer.
Constitutional Law Professor Seeks To Skirt The Constitution
Virginia Senator Moran In Solid Support
By Dell Hill
Sometimes
they let their guard down and reveal their true allegiance. I’m
talking about far-left leaning Democrats - the ones we generally refer
to as Marxist socialists.
It
happened again recently. Virginia Democratic Rep. Jim Moran told The
Daily Caller on Thursday evening that President Obama should “refinance
every home mortgage” without congressional approval in order to “reset
the economy.”
But don’t take my word for it; watch the video from the Daily Caller:
The
Senator from Virginia is quite obviously sober and has his wits about
him as he suggests the President take unilateral action that’s
diametrically opposed to the separation of powers under the
constitution.
And don’t be shocked if the President tries to do just that!
Obama has already asked
his Council on Jobs to identify areas of the American Jobs Act that can
be implemented without congressional authorization, clearly showing his
personal frustration with his political opponents across the aisle in
congress and a willingness to take on dictatorial powers to achieve his
goals.
All of this from a man whom we are told taught a college level course in Constitutional Law?
It’s Time To Reject The Socialist RegimeObama’s Money Laundering Political Machine Must Be StoppedBy Dell HillVia Doug Ross @ JournalWhen
it comes to in-depth analysis, Doug Ross consistently produces must
read material. Very early in my blog writing experience, the late Jane
Jamison introduced me to Doug’s blog - Doug Ross@Journal
- and suggested it as an example of the kind of articulate,
well-researched blog posting that she hoped to achieve at
Uncoverage.net. It certainly didn’t take long before I was in total
agreement.I
very much appreciate the fact that you’re reading my blog right now,
but I hope you’ll take the time to visit Doug’s web site and peruse his
excellent offerings.This
particular piece struck me as the type of political information that
every American voter should seriously consider in the run-up to the 2012
presidential elections. It is reprinted in its entirety with
permission.
A
year in advance of the momentous 2012 elections, it's worth revisiting
the 2008 campaign that brought Barack Obama to power. In particular,
the Obama campaign took an unprecedented series of steps to allow
illegal campaign contributions and electronic money laundering. intentionally turned off all credit-card security,
which allowed the entry of fake names and addresses for donations.
Obama's 2008 fundraising website intentionally allowed this to occur. accepted made-up credit-card numbers,
which were probably tried one after another until valid card numbers
were found. Obama's 2008 fundraising website intentionally allowed this
to occur. retained forged computer addresses for its donations instead of the addresses of the real donors. Obama's 2008 fundraising website intentionally allowed this to occur. accepted untraceable prepaid cash cards
that could easily have been used to evade contribution limits or mask
contributor identities. Obama's 2008 fundraising website intentionally
allowed this to occur. secretly shared donor lists with Project Vote and ACORN, the latter a group reportedly under a RICO investigation
for multi-state vote fraud involving hundreds of thousands of
fraudulent registrations and other misdeeds. Obama's 2008 fundraising
operation allegedly did just that.IP addresses).
In my opinion, there is only one reason a website would allow the
submission of a fake IP address: money-laundering. Logging of the true
IP address would mean that the real source (including the city and
country) of the contribution could be traced. Allowing a fake address
to be logged instead would prevent authorities from ascertaining the
true origin of the donation.In
2012, I urge you to be on the look-out for this kind of diabolical
rule-breaking as a desperate Democrat Party scrabbles to hold onto
power.Copyright © 2003-2011 by Doug Ross, All Rights Reserved. Reprinted with permission.Note From Dell Hill: My thanks to Doug Ross for allowing me to reprint this entire piece. The
subject matter - the 2012 presidential election - will be, without
question, the most important election in this nation’s 236 year history.
Over the past three years we’ve helplessly watched as our country is
being dramatically converted from a highly successful Capitalist nation
into a socialist regime, reminiscent of the failed Marxist Union of
Soviet Socialist Republics. We simply can’t let that happen.It’s
time to reject Barack Obama and his socialist regime. And not only
Obama. Every Senator and Representative who supports this President’s
socialist agenda, who are bent on destroying this country, should be
turned out of office by the very power that has made the United States
the greatest country on Earth - We, the people.
President’s Super Committee Is TemptedBy Dell HillPublisher’s
Note: This blog does not give financial advice of any kind. Opinions
expressed here are solely those of the writers identified and linked so
as to better educate our readers. Please consult your personal
investment counselor(s) for your particular investment decisions.With
a super committee desperately searching for a fair method of extracting
$1.5 trillion dollars in deficit cuts, some very low-hanging fruit has
emerged. And there’s been talk about this possibility for some time.
The problem now is time. The President’s super committee has until
December to come up with a plan and, thus far, most of the talk has
centered around reconnoitering 401-Ks and IRAs for a substantial tax
hit.JOHN MERLINE, writing at INVESTOR'S BUSINESS DAILY, brings us up to date on the latest.
Senate Finance Committee Chairman Max Baucus, D-Mont.“Is
your 401(k) safe from the tax man? That's a question that might be
worth asking, as the congressional "supercommittee" scrambles to find
$1.5 trillion in additional deficit cuts.In
September, the Senate Finance Committee held a little-noticed hearing
that explored changes to retirement plans — principally
employer-sponsored 401(k)s — that would in one way or another cut their
tax deductions.The
tax breaks' size makes them a tempting target for lawmakers. According
to the White House budget office, tax exemptions for 401(k)s and IRAs
will "cost" the government more than $436 billion over the next five
years.Senate
Finance Committee Chairman Max Baucus, D-Mont., complained that "in
spite of the tremendous tax preferences," Americans aren't saving nearly
enough for retirement.Critics
say the existing system benefits mostly the rich. The liberal-leaning
Tax Policy Center calculates that 80% of these tax "expenditures" go to
the top 20% of earners. Such
people "would almost certainly save for retirement even without tax
incentives," said Karen Friedman, policy director at the Pension Rights
Center.But
Judy Miller of the American Society of Pension Professionals and
Actuaries argues that the deduction's cost is wildly exaggerated.
Adjust for the taxes paid when retirees withdraw money and the cost is
cut in half.And,
she says, the break is more progressive than some allege. Among other
things, high earners who get a bigger tax break going in end up paying
more in taxes when they take the money out."Contrary
to the common myth, the tax incentives are not upside down at all," she
said at the Senate hearing. Plus, the current system has led to an
explosion in retirement savings, with 401(k)s now holding about $4.7
trillion in assets and IRAs $4.9 trillion.Still,
proposals to cut the deduction and make it more "fair" seem to be
gaining traction in Washington, including the White House.One
idea pitched at the Senate hearing is to replace the entire tax
deduction with a flat government match of 18% to 30%. The Brookings
Institution's William Gale, who helped develop the idea, says if the
credit were set at 18%, it would boost tax revenues by $458 billion over
10 years, mostly from wealthier workers.President
Obama's debt commission proposed cutting the annual cap on 401(k)
employer/employee combined contributions to $20,000 from $49,000 now.
(The individual limit is $16,500 a year; workers age 50 and older can
add another $5,000).I realize that what you’ve read thus far is a pretty big bite to chew. But if you’re serious about your retirement earnings, read the rest of this report by clicking here.For
me, what it all boils down to is a lot of “maybe”, mixed with a
generous amount of concern. Having full knowledge of the incredible
shenanigans that resulted in Obamacare becoming law, I no longer trust
anyone who holds public office to advise me on my finances, nor do I
have any confidence that my retirement accounts are safe from the
Democrats tax and spend thievery. You can throw a few RINO Republicans
into that mix, as well.Just
the fact that we’re talking and writing about this possibility is
frightening enough. Consult your financial manager and keep both eyes
peeled on Washington, D.C.